What Is the Lifespan for Domestic Rabbits? Do Spayed Or Neutered Rabbits Live Up to 15 Years In Good Health? Do Smaller Rabbits Have a Longer Lifespan? At BackyardBunnyNews, we help people who want to raise rabbits and bunnies by collating information about the hare-raising experience. In good health, a domestic rabbit can live for up to 15 years if it is neutered or spayed. Wild rabbits tend to live longer. Listed below are the typical lifespans of some domestic rabbit breeds. Keep in mind that their lifespan will vary based on their age and health conditions.